Sunday, May 31, 2015

TBI 1. Neurologic Assessment, Consultation, Re-imaging and Admission (BIGs)




University of Kentucky / UK HealthCare
Departments of Surgery, Emergency Medicine, Anesthesiology, and Neurosurgery

 Management Protocol
Title/Description: Brain Injury Guidelines (BIG) for Traumatic Brain Injury
Purpose: Provide practice guidelines for evaluation, consultation, and management of Traumatic Brain Injury

Background

1.     There is limited background for standardized guidelines on assessment and management of immediate Traumatic Brain Injury (TBI).

2.     TBI requires a multidisciplinary team for appropriate utilization of resources, and consultation of services.

Recent studies have developed protocols for safe and appropriate diagnosis and management of TBI.  The Brain Injury Guidelines (BIG) protocol has been assessed in large volume studies.1  The following Table classifies the diagnosis and treatment of different types of TBI based on BIG categories.  In a study of 1232 patients with abnormal head CT (among a cohort of 3803 TBI patients), BIG 1 assessement and treatment resulted in no clinical/radiographic worsening with no intervention required.  BIG 2 patients had radiographic worsening in 2.6% of patients.  All neurosurgical interventions were in BIG 3 patients. 




Table 1.  BIG Protocol
Patient Selection
The BIG protocol will be applied to any adult (16 years or older) with TBI ranging from mild (concussion) to severe. 

Protocol

Patients will be assessed and managed per the protocol outlined in Table 1.
Additional clinical management issues are clarified below:

1.     Neurosurgery will see patients with abnormal head CT and GCS < 8 within 30 minutes of notification.

2. Seizure prophylaxis (Keppra or Dilantin) is recommended for 7 days for any patient with intraparenchymal hemorrhage (intracranial or intraventricular hemorrhage) of any size or BIG 3.  However, if the patient has a witnessed seizure please consult Neurosurgery and Neurology.

3.     It is not clinically indicated to hold NSAIDs if they are recommended for other pathology in the patient.

4.     DVT prophylaxis is recommended starting at 24 hours after admission for BIG 1, and 48 hours after admission for BIG 2.  For BIG 3, please request clarification from Neurosurgery service.

5.     Defer to Neurosurgery service for questions regarding holding/restarting of anticoagulation medications.

6.     All BIG classifications should followup in Trauma (Blue) clinic after discharge.  Patients who have undergone neurosurgical intervention should also followup with Neurosurgery.  Patients discharged on continuing anti-epileptic medications (beyond 7 days) should followup with Neurology.

7.     Post-TBI symptoms that continue beyond 90 days or clinically worsen after discharge should result in referral to Cardinal Hill Rehabilitation Hospital TBI Clinic.

Communication and Adherence
These guidelines are not intended as a directive or to present a definitive statement of the applicable standard of patient care. They are offered as an approach for quality assurance and risk management and are subject to (1) revision as warranted by the continuing evaluation of technology and practice; (2) the overall individual professional discretion and judgment of the treating provider in a given patient circumstance; and (3) the patient’s willingness to follow the recommended treatment.

Any questions about a patient’s candidacy for management under this protocol should result in a multidisciplinary communication, most notably between the Trauma (Blue) Service and Neurosurgery Service.

Concerns about the protocol and its application should be addressed to Andrew Bernard at andrew.bernard@uky.edu.


REFERENCES


1.         Joseph B, Friese RS, Sadoun M, Aziz H, Kulvatunyou N, Pandit V, et al. The big (brain injury guidelines) project: Defining the management of traumatic brain injury by acute care surgeons. J Trauma Acute Care Surg. 2014;76:965-969


Glasgow Coma Score (Updated 2014)

Eye Opening
Verbal
Motor
6


Obeys Commands
5

Oriented
Localizes
4
Spontaneous
Confused
Normal Flexion
3
To Sound
Words
Abnormal Flexion
2
To Pressure
Sounds
Extension
1
None
None
None
Key points:
Give EMV in individual scores, not summative GCS (note many other centers report EVM, not EMV).
Give a number for verbal if talking around their ETT/Trach.
Assessment for painful stimuli:  axillary pectoral muscle pinch.
Assessment for spinal cord reflex:  nailbed pressure

Admit Location
Multi-system severely injured patients are generally admitted to 7-100 and 7-200.
Isolated or primary severe TBI patients are generally admitted to 6-200.

Imaging
See Trauma Imaging and Concussion Guidelines: